Annals of Clinical Nutrition and Metabolism

Table. 2. Table 2

Changes in microbiota composition after probiotic/synbiotic treatment

Author	Probiotics/synbiotics		Control

	Increase	Decrease	Increase	Decrease
Synbiotics
Kanazawa et al. [16]	Lactobacillus, Bifidobacteriuma Enterococci		Enterobacteriaceae, Pseudomonas, Candida^a, Enterococci
Sugawara et al. [17]	Lactobacillus, Bifidobacterium^a	Candida
Eguchi et al. [36]	No significant difference between groups
Usami et al. [12]	Candida	Bacteroidaceae, Bifidobacterium
Tanaka et al. [13]	Bifidobacterium, Lactobacillus^b	Enterobacteriaceae^a
Okazaki et al. [14]	Bifidobacterium^a	Enterobacteriaceae, Staphylococcus^a		Bifidobacterium
Komatsu et al. [33]	Clostridium leptum subgroup, Bifidobacterium, Lactobacillus^a	Enterobacteriaceae, Staphylococcus, Pseudomonas^a	Enterobacteriaceae, Staphylococcus, Pseudomonas, Clostridium difficile^a	Clostridium coccoides group, Clostridium leptum subgroup, Bacteroides fragilis group, Bifidobacterium, Prevotella, Lactobacillus^a
Yokoyama et al. [28]	Bifidobacterium, Lactobacillus^a	Enterobacteriaceae, Pseudomonas^a	Pseudomonas, Staphylococcus, Enterobacteriaceae^a
Probiotics
Liu et al. [18]	Bifidobacterium^a, Enterococci	Enterobacteriaceae, Pseudomonas, Candida^a	Enterobacteriaceae, Pseudomonas, Candida^a, Enterococci
Zhang et al. [15]	Bifidobactrium longum^b	Escherichia coli^b	Bifidobacterium–Escherichia coli ratio inversion^b
Grąt et al. [39]	Enterococcus^a, Lactobacillus

^a,bStatistically significant comparing with control group (^aP<0.05, ^bP<0.01).