Fig. 2. Assessments of muscle protein fractional synthetic rate using amino acid (AA) tracer method. Both labeled tracer and unlabeled AAs cross the muscle cell membrane in proportion to their relative concentrations (i.e., tracer-to-tracee ratio) to enter the free AA precursor pool from where they are either oxidized or incorporated into proteins. For a given precursor enrichment, a greater labeling of product (i.e., protein enrichment) is achieved in the faster synthesis condition (A) compared with the slower synthesis condition (B). This figure was created with BioRender.com.
MPS = muscle protein synthesis; MPB = muscle protein breakdown.
© 2022 Ann Clin Nutr Metab