Rates of change in body composition in elderly and non-elderly patients
| Variable | Baseline | 6 months | 12 months | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Non-elderly (n=164) | Elderly (n=69) | Non-elderly (n=143) | Elderly (n=61) | P-value | Non-elderly (n=135) | Elderly (n=48) | P-value | |||
| ICW (L) | 23.7±17.1 | 19.8±3.7 | –3.3±9.2 | –3.5±9.9 | 0.879 | –2.5±10.1 | –1.9±7.6 | 0.712 | ||
| ECW (L) | 14.7±10.1 | 12.7±2.4 | –1.7±8.4 | –0.9±8.0 | 0.543 | –0.6±10.5 | 0.1±7.0 | 0.654 | ||
| Protein (kg) | 10.3±7.4 | 8.5±1.6 | –3.4±8.8 | –2.7±8.7 | 0.593 | –2.8±9.5 | –3.4±14.2 | 0.756 | ||
| Mineral (kg) | 3.3±0.7 | 2.9±0.5 | –0.9±8.6 | –0.2 ±10.5 | 0.629 | 0.7±9.4 | 1.1±10.5 | 0.846 | ||
| BW (kg) | 66.9±11.2 | 61.9±12.4 | –9.27±11.3 | –8.3±11.7 | 0.579 | –9.0±6.5 | –8.0±10.5 | 0.449 | ||
| BMI (kg/m2) | 24.5±3.2 | 24.0±3.6 | –8.4±7.1 | –7.0±12.1 | 0.285 | –9.0±6.6 | –6.8±11.4 | 0.106 | ||
| SMM (kg) | 28.9±22.3 | 23.7±4.9 | –3.7±9.4 | –3.1±9.3 | 0.697 | –2.8±9.8 | –2.0±8.3 | 0.614 | ||
| BFM (kg) | 18.3±13.4 | 18.1±7.6 | –23.4±21.8 | –26.5±20.6 | 0.362 | –28.1±27.5 | –26.8±28.2 | 0.776 | ||
| PBF (%) | 26.0±8.7 | 29.0±8.0 | –16.8±21.6 | –17.1±23.5 | 0.928 | –20.9±25.5 | –21.6±27.1 | 0.874 | ||
| LBM (kg) | 49.5±10.0 | 43.8±8.2 | –2.3±5.4 | –2.1±8.4 | 0.826 | –1.5±6.1 | –1.1±7.4 | 0.718 | ||
| BCM (kg) | 32.1±6.6 | 28.2±5.4 | –2.9 ±5.6 | –2.9 ±8.6 | 0.962 | –2.0±6.2 | –1.8±7.7 | 0.854 | ||
| BMC (kg) | 2.7±0.6 | 2.4±0.4 | –0.7±9.3 | 0.4 ±10.9 | 0.489 | 1.2±9.9 | 1.8±10.7 | 0.744 | ||
| VFA (cm2) | 77.6±37.3 | 87.0±42.3 | –19.7±30.7 | –20.0±32.2 | 0.943 | –29.7±30.3 | –24.3±36.5 | 0.323 | ||
| BMR (kcal) | 1,448.6±177.9 | 1,316.0±177.9 | –1.7±7.5 | –1.5±6.1 | 0.823 | –1.8±11.5 | –0.8±5.3 | 0.534 | ||
Values are presented as mean±standard deviation.
ICW = intracellular water; ECW = extracellular water; BW = body weight; BMI = body mass index; SMM = skeletal muscle mass; BFM = body fat mass; PBF = percent body fat; LBM = lean body mass; BCM = body cell mass; BMC = bone mineral content; VFA = visceral fat area; BMR = basal metabolic rate.