Fig. 3. Association between creatinine and skeletal muscle index (SMI) and overall survival according to sex using a restricted cubic spline regression model. Graphs show hazard ratios for overall survival according to creatinine (A) and SMI (B) of each sex adjusted for sex. Data were fitted by a restricted cubic spline Cox proportional hazards regression model, and the model was conducted with 4 knots at the 5th, 35th, 65th, and 95th percentiles of creatinine and SMI (reference is the 5th percentile). Solid lines indicate hazard ratios, and shadow shape indicates the 95% confidence interval (CI).
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